Kristin Krukenberg

Email: Kristin_Krukenberg * hms.harvard.edu

Publications Krukenberg KA, Bottcher UM, Southworth DR, Agard DA. Grp94, the endoplasmic reticulum Hsp90, has a similar solution conformation to cytosolic Hsp90 in the absence of nucleotide. Protein Sci. 2009 Sep;18(9):1815-27. PubMed Krukenberg KA, Southworth DR, Street TO, Agard DA. pH-dependent conformational changes in bacterial Hsp90 reveal a Grp94-like conformation at pH 6 that is highly active in suppression of citrate synthase aggregation. J Mol Biol. 2009 Jul 10;390(2):278-91. Epub 2009 May 7. PubMed Forster F, Webb B, Krukenberg KA, Tsuruta H, Agard DA, Sali A. Integration of small-angle X-ray scattering data into structural modeling of proteins and their assemblies. J Mol Biol. 2008 Oct 17;382(4):1089-106. Epub 2008 Jul 31. PubMed Cunningham CN, Krukenberg KA, Agard DA. Intra- and intermonomer interactions are required to synergistically facilitate ATP hydrolysis in Hsp90. J Biol Chem. 2008 Jul 25;283(30):21170-8. Epub 2008 May 20. PubMed Multiple conformations of E. coli Hsp90 in solution: insights into the conformational dynamics of Hsp90. Comment in: Structure. 2008 May;16(5):659-61. Structure. 2008 May;16(5):755-65. PubMed Kung C, Kenski DM, Krukenberg K, Madhani HD, Shokat KM. Selective kinase inhibition by exploiting differential pathway sensitivity. Chem Biol. 2006 Apr;13(4):399-407. PubMed Zolman BK, Monroe-Augustus M, Thompson B, Hawes JW, Krukenberg KA, Matsuda SP, Bartel B. chy1, an Arabidopsis mutant with impaired beta-oxidation, is defective in a peroxisomal beta-hydroxyisobutyryl-CoA hydrolase. J Biol Chem. 2001 Aug 17;276(33):31037-46. Epub 2001 Jun 12. PubMed