Yangzhong Tang I'm interested in studying the mechanism of how an Eg5 inhibitor induces a rapid apoptotic response of HL60, a promyelocytic leukemia cell line.

Email: yangzhong_tang * hms.harvard.edu

Publications Orth JD, Tang Y, Shi J, Loy CT, Amendt C, Wilm C, Zenke FT, Mitchison TJ. Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate. Mol Cancer Ther. 2008 Nov;7(11):3480-9. Epub 2008 Oct 30. PubMed Craciun G, Tang Y, Feinberg M. Understanding bistability in complex enzyme-driven reaction networks. Proc Natl Acad Sci U S A. 2006 Jun 6;103(23):8697-702. Epub 2006 May 30. PubMed Tang Y, Feinberg M. Carnot-like Limits to Steady-State Productivity. Ind. Eng. Chem. Res. 2007 Aug 15; 46(17): 5624-5630.