Aaron Groen

Email: aaron_groen * student.hms.harvard.edu

Publications Maresca TJ, Groen AC, Gatlin JC, Ohi R, Mitchison TJ, Salmon ED. Spindle Assembly in the Absence of a RanGTP Gradient Requires Localized CPC Activity. Curr Biol. 2009 Jun 17; [Epub ahead of print] PubMed Groen AC, Maresca TJ, Gatlin JC, Salmon ED, Mitchison TJ. Functional overlap of microtubule assembly factors in chromatin-promoted spindle assembly. Mol Biol Cell. 2009 Jun;20(11):2766-73. Epub 2009 Apr 15. PubMed Wuhr M, Dumont S, Groen AC, Needleman DJ, Mitchison TJ. How does a millimeter-sized cell find its center? Cell Cycle. 2009 Apr 9;8(8) [Epub ahead of print] PubMed Gatlin JC, Matov A, Groen AC, Needleman DJ, Maresca TJ, Danuser G, Mitchison TJ, Salmon ED. Spindle fusion requires dynein-mediated sliding of oppositely oriented microtubules. Curr Biol. 2009 Feb 24;19(4):287-96. PubMed Wuhr M, Chen Y, Dumont S, Groen AC, Needleman DJ, Salic A, Mitchison TJ. Evidence for an upper limit to mitotic spindle length. Curr Biol. 2008 Aug 26;18(16):1256-61. PubMed Groen AC, Needleman D, Brangwynne C, Gradinaru C, Fowler B, Mazitschek R, Mitchison TJ. A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly. J Cell Sci. 2008 Jul 15;121(Pt 14):2293-300. Epub 2008 Jun 17. PubMed Burbank KS, Groen AC, Perlman ZE, Fisher DS, Mitchison TJ. A new method reveals microtubule minus ends throughout the meiotic spindle. J Cell Biol. 2006 Nov 6;175(3):369-75. PubMed Ribbeck K, Groen AC, Santarella R, Bohnsack MT, Raemaekers T, Kocher T, Gentzel M, Gorlich D, Wilm M, Carmeliet G, Mitchison TJ, Ellenberg J, Hoenger A, Mattaj IW. NuSAP, a Mitotic RanGTP Target That Stabilizes and Cross-links Microtubules. Mol Biol Cell. 2006 Mar 29; [Epub ahead of print] PubMed Mitchison TJ, Maddox P, Gaetz J, Groen A, Shirasu M, Desai A, Salmon ED, Kapoor TM. Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles. Mol Biol Cell. 2005 Jun;16(6):3064-76. Epub 2005 Mar 23. PubMed Miyamoto DT, Perlman ZE, Burbank KS, Groen AC, Mitchison TJ. The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles. J Cell Biol. 2004 Dec 6;167(5):813-8. PubMed Groen AC, Cameron LA, Coughlin M, Miyamoto DT, Mitchison TJ, Ohi R. XRHAMM functions in ran-dependent microtubule nucleation and pole formation during anastral spindle assembly. Curr Biol. 2004 Oct 26;14(20):1801-11. PubMed Full Text Mitchison TJ, Maddox P, Groen A, Cameron L, Perlman Z, Ohi R, Desai A, Salmon ED, Kapoor TM. Bipolarization and poleward flux correlate during Xenopus extract spindle assembly. Mol Biol Cell. 2004 Dec;15(12):5603-15. Epub 2004 Sep 22. PubMed Sekiya-Kawasaki M, Groen AC, Cope MJ, Kaksonen M, Watson HA, Zhang C, Shokat KM, Wendland B, McDonald KL, McCaffery JM, Drubin DG. Dynamic phosphoregulation of the cortical actin cytoskeleton and endocytic machinery revealed by real-time chemical genetic analysis. J Cell Biol. 2003 Sep 1;162(5):765-72. PubMed Watson HA, Cope MJ, Groen AC, Drubin DG, Wendland B. In vivo role for actin-regulating kinases in endocytosis and yeast epsin phosphorylation. Mol Biol Cell. 2001 Nov;12(11):3668-79. PubMed