Peg Coughlin

Email: margaret_coughlin * hms.harvard.edu

Publications Chang P, Coughlin M, Mitchison TJ. Interaction between Poly(ADP-ribose) and NuMA Contributes to Mitotic Spindle Pole Assembly. Mol Biol Cell. 2009 Sep 16; [Epub ahead of print] PubMed Hu CK, Coughlin M, Field CM, Mitchison TJ. Cell polarization during monopolar cytokinesis. J Cell Biol. 2008 Apr 21;181(2):195-202. Epub 2008 Apr 14. PubMed Charras GT, Coughlin M, Mitchison TJ, Mahadevan L. Life and Times of a Cellular Bleb. Biophys J. 2007 Oct 5; [Epub ahead of print] PubMed Charras GT, Hu CK, Coughlin M, Mitchison TJ. Reassembly of contractile actin cortex in cell blebs. J Cell Biol. 2006 Nov 6;175(3):477-90. PubMed Chang P, Coughlin M, Mitchison TJ. Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function. Nat Cell Biol. 2005 Oct 23; [Epub ahead of print] PubMed Groen AC, Cameron LA, Coughlin M, Miyamoto DT, Mitchison TJ, Ohi R. XRHAMM functions in ran-dependent microtubule nucleation and pole formation during anastral spindle assembly. Curr Biol. 2004 Oct 26;14(20):1801-11. PubMed Full Text Brieher WM, Coughlin M, Mitchison TJ. Fascin-mediated propulsion of Listeria monocytogenes independent of frequent nucleation by the Arp2/3 complex. J Cell Biol. 2004 Apr 26;165(2):233-42. PubMed Full Text Ohi R, Coughlin ML, Lane WS, Mitchison TJ. An inner centromere protein that stimulates the microtubule depolymerizing activity of a KinI kinesin. Dev Cell. 2003 Aug;5(2):309-21. PubMed Full Text Maddox P, Straight A, Coughlin P, Mitchison TJ, Salmon ED. Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics. J Cell Biol. 2003 Aug 4;162(3):377-82. PubMed Full Text Shirasu-Hiza M, Coughlin P, Mitchison T. Identification of XMAP215 as a microtubule-destabilizing factor in Xenopus egg extract by biochemical purification. J Cell Biol. 2003 Apr 28;161(2):349-58. PubMed Self- and actin-templated assembly of Mammalian septins. Comment in: Dev Cell. 2002 Dec;3(6):761-3. Dev Cell. 2002 Dec;3(6):791-802. PubMed Full Text Kapoor TM, Mayer TU, Coughlin ML, Mitchison TJ. Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5. J Cell Biol. 2000 Sep 4;150(5):975-88. PubMed Taunton J, Rowning BA, Coughlin ML, Wu M, Moon RT, Mitchison TJ, Larabell CA. Actin-dependent propulsion of endosomes and lysosomes by recruitment of N-WASP. J Cell Biol. 2000 Feb 7;148(3):519-30. PubMed